Product Profile

Product Name	Anti-YAP1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	YAP1
Gene Synonyms	YAP YKI COB1 YAP2 YAP65 Hide
Gene Full Name	Yes1 associated transcriptional regulator
Gene Summary	This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] Hide
Molecular Weight(MW)	54 kDa
Source	Rabbit
Cellular Localizatio	Cytoplasm, Nucleus

Application

       

WB

Western blot analysis using YAP1 antibdoy against Caco-2 (1), KATOⅢ (2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using YAP1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of NIH/3T3 cells using YAP1 antibody(green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.