Product Profile

Product Name	Anti-PCNA antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHC
	IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	PCNA
Gene Synonyms	ATLD2
Gene Full Name	proliferating cell nuclear antigen
Gene Summary	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008] Hide
Source	Rabbit
Cellular Localizatio	Nucleus

Application

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PCNA antibody with DAB staining.

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IHC

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using PCNA antibody with DAB staining.

Application Notes

IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.