Product Profile

Product Name	Anti-NTRK1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	NTRK1
Gene Synonyms	MTC TRK TRK1 TRKA p140-TrkA DKFZp781I14186 NTRK1 Hide
Gene Full Name	neurotrophic receptor tyrosine kinase 1
Gene Summary	This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	87 KDa
Source	Rabbit
Cellular Localizatio	Plasma membrane,Endosome

Application

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WB

Western blot analysis using NTRK1 antibody against Jurkat (1) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using NTRK1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of HepG2 cells using NTRK1 antibody(green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.