Product Profile

Product Name	Anti-SOX10 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	SOX10
Gene Synonyms	DOM WS4 PCWH WS2E WS4C SOX-10 More
Gene Full Name	SRY-box transcription factor 10
Gene Summary	This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008] More
Molecular Weight(MW)	50 kDa
Cellular Localizatio	SRY-box transcription factor 10

Application

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WB

Western blot analysis using SOX10 antibody against NIH/3T3(1), PC-12(2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using SOX10 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of SK-OV-3 cells using SOX10 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.