Product Profile

Product Name	Anti-LXN antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	LXN
Gene Synonyms	ECI TCI
Gene Full Name	latexin
Gene Summary	This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020] Hide
Molecular Weight(MW)	26kD(Observed:35 kD）
Cellular Localizatio	Cytoplasm

Application

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WB

Western blot analysis using LXN antibody against Hek293(1), Hela(2), HepG2(3), A431(4) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using LXN antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of A549 cells using LXN antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.