Product Profile

Product Name	CREB Antibody (S129)
Antibody Type	Primary Antibodies

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB~~1:500~1:1000:
Species Reactivity	Human
Concentration	1 mg/ml
Purification

Target Information

Alternative Names	Cyclic AMP-responsive element-binding protein 1 cAMP-responsive element-binding protein 1 CREB-1
Molecular Weight(MW)	36688 Da
Function	Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells More
Tissue Specificity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Cellular Localization	Nucleus.

Database Links

Entrez Gene

1385

Application

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Application

Western blot analysis of extracts from 293 cells untreatedor treated with UV, using CREB Antibody (S129)(#AE1010a, Lane 1 and 2) and Phospho-CREB-S129 Antibody (#AE1010c, Lane 3 and 4).

Application Notes

WB~~1:500~1:1000:

Additional Information

Form	Liquid
Storage Instructions	For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.