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- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-09-14
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | 电询 |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Claudin 5 (phospho Tyr217) Antibody
Antibody Type
Primary Antibodies
Product
description
This gene
encodes a member of the claudin family. Claudins are integral membrane
proteins and components of tight junction strands. Tight junction strands
serve as a physical barrier to prevent solutes and water from passing freely
through the paracellular space between epithelial or endothelial cell sheets.
Mutations in this gene have been found in patients with velocardiofacial
syndrome.1) Sirotkin H., Genomics 42:245-251(1997).
Hide
Immunogen
Claudin 5
(phospho Tyr217) antibody was raised against a peptide sequence around
phosphorylation site of tyrosine 217 (K-K-N-Y (p)-V) derived from Human
Claudin 5.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Applications
IHC
IHC:1:50~1:200
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
CLDN5
Alternative
Names
CLD5
Molecular
Weight(MW)
23 kDa
Tissue
Specificity
The antibody detects endogenous levels of
Claudin 5 only when phosphorylated at tyrosine 217.
Database Links
Entrez Gene
7122
Protein
Accession
NP_001124333.1
Application
Notes:Optimal dilutions/concentrations should be determined by the
researcher.
CLDN5
TMDVCF
·
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 (Phospho-Tyr217) antibody (left) or the same antibody preincubated with blocking peptide (right).
|
Application Notes |
IHC:1:50~1:200 |
Additional Information
|
Form |
Liquid |
|
Storage Instructions |
Store antibody at -20?C for up to one year. |
|
Storage Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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