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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Histone H3.3 antibody
Antibody Type
Primary Antibodies
Product
description
Rabbit
Monoclonal antibody [RM190] to Histone H3.3Histones are basic nuclear
proteins that are responsible for the nucleosome structure of the chromosomal
fiber in eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is
wrapped in repeating units, called nucleosomes. The linker histone, H1,
interacts with linker DNA between nucleosomes and functions in the compaction
of chromatin into higher order structures. This gene contains introns and its
mRNA is polyadenylated, unlike most histone genes. The protein encoded is a
replication-independent member of the histone H3 family. [provided by RefSeq,
Jul 2008]
More
Immunogen
A peptide
corresponding to human Histone H3.3.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Clone Number
RM190
Host Species
Rabbit
Tested
Applications
ELISAWBMultiplexing
WB:1:500~1:2000
Species
Reactivity
Human
Concentration
1 mg/ml (Please refer to the vial label
for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
H3.3A
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Target
Histone H3.3
Tissue
Specificity
This antibody reacts to Histone H3.3,
independent of post-translational modifications. No cross reactivity with
Histone H3.1 or other histone proteins.
Application
Notes:Optimal dilutions/concentrations should be determined by the
researcher.
H3 histone
family 3A
H3F3A
H3F3
Histone H3.3 antibody
·
Application
Western Blot of HeLa whole cell lysate, recombinant Histone H3.3 and Histone H3.1 proteins, using RM190 at 1 ug/mL, showed a band of histone H3.3 in HeLa cells and recombinant H3.3 protein, and no cross activity with Histone H3.1.
·
Application
RM190 reacts specifically to Histone H3.3. No cross reactivity with Histone H3.1.
Application Notes |
WB:1:500~1:2000 |
Additional Information
Form |
Liquid |
Storage Instructions |
Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer |
PBS with 50% Glycerol and 1% BSA. 0.09% Sodium azide was added as a preservative. |