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消息:硫酸葡聚糖 钠盐 来源于明串珠菌 属@2024资料文献已更新
  • 品牌:DUMABIO
  • 产地:上海
  • 型号:1mg
  • 货号:电询
  • 发布日期: 2024-01-26
  • 更新日期: 2026-01-19
产品详请
产地 上海
保存条件 密封于-20oC阴凉干燥环境。
品牌 DUMABIO
货号 电询
用途 科研与实验
检测方法 电询
保质期 2年
适应物种 电询
检测限 电询
数量 1000
包装规格 1mg
标记物
样本 电询
应用 科研试剂
是否进口

消息:硫酸葡聚糖 钠盐 来源于明串珠菌 属@2024资料文献已更新


别名:6-O-(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-D-glucose, Manninotriose


CAS号:9011-18-1


MDL编号:MFCD00081551


NACRES:NA.31


生物来源
synthetic

等级
for molecular biology

形式
powder

分子量
average Mw >500,000 (dextran starting material)

包含
0.5-2% phosphate buffer

组成
Sulfur Content, 16.0-19.0%

technique(s)
FISH: suitable
FTIR: suitable

颜色
off-white

useful pH range
6.0-8 (10 g/L)

溶解性
H2O: 100 mg/mL

适用性
suitable for marker for electrophoresis
suitable for nucleic acid hybridization

application(s)
genomic analysis
sample preparation

储存温度
2-8°C

一般描述
Dextran sulfate sodium (DSS) is a synthetic sulfated derivative of dextran, a complex polysaccharide composed of glucose molecules. DSS is characterized as a biocompatible, highly branched polysaccharide with 1–6 and 1–4 glycosidic linkages, featuring approximately 2.3 sulfate groups per glucosyl unit. Dextran sulfate is a sulfated polysaccharide with a variable molecular weight ranging from 5 to 1,400 kDa. It finds extensive use in molecular biology and biochemical research, with a particular emphasis on gastrointestinal investigations.DSS is widely recognized for its ability to induce colonic inflammation in mouse models of inflammatory bowel disease (IBD). It is widely recognized for its capacity to induce colonic inflammation in mouse models of inflammatory bowel disease (IBD) by creating models of acute, chronic, and relapsing IBD, by adjusting its concentration and administration frequency. Furthermore, Dextran sulfate is applied in various molecular biology techniques, such as precipitating lipoproteins, accelerating DNA probe hybridization, and facilitating ribosomal isolations. Notably, DSS serves as a valuable cross-linker for chitosan, allowing for the creation of microparticles and nanoparticles used in controlled drug delivery systems. Beyond these applications, DSS plays a central role in diverse research areas, particularly immunology and virology, where it actively modulates immune responses, enhances humoral immunity, influences B-lymphocyte activation, and affects thymocyte reactivity to lectins.


消息:硫酸葡聚糖 钠盐 来源于明串珠菌 属@2024资料文献已更新

应用
葡聚糖硫酸酯具有许多用途,当进行核酸杂交时可用作缩短探针退火所需时间的促进剂。当杂交速率成为检测稀有序列的限制因子时或当可用探针数量有限时,可在杂交缓冲液中加入葡聚糖硫酸酯。葡聚糖硫酸酯通过从聚合物所占溶液体积中扣除核酸而发挥促进剂的作用,从而提高有效的探针浓度。
Dextran sulfate has been used

as a molecular weight marker to assess the purity and homogeneity of the purified polysaccharides by gel electrophoresis[1]
as a component of the hybridization buffer in fluorescence in situ hybridization (FISH) protocol for DNA detection and analysis[2][3]
生化/生理作用
Dextran sulfate, being a sulfated polysaccharide, consistently triggers experimental acute and chronic colitis. It is believed to initiate mucosal injury and inflammation, primarily through a direct toxic impact on epithelial cells. This initial effect activates macrophages and T lymphocytes, ultimately leading to cytokine-mediated cytotoxicity.
特点和优势
Suitable for Nucleic acid hybridization & Molecular Biology
Dextran Sulfate with an average molecular weight of >500,000
Sulfur Content of 16.0-19.0 %
Versatile and adaptable for wide variety of laboratory and research applications

适用性
已测试了在核酸杂交中的适应性
其他说明
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.



IF<5,赠送价值 500元礼品卡
5 ≤IF≤10,赠送价值 1000元礼品卡
IF≥10,赠送价值 1000元礼品卡+任意 1 款 ValukineTM 试剂盒


DUMABIO ELISA试剂盒文献征集奖励活动

为感谢各位老师对笃玛品牌的支持与厚爱,凡购买DUMABIO ELISA试剂盒,在SCI期刊杂志发表文中注明ELISA试剂盒采购上海笃玛生物科技有限公司(Shanghai DuMa Biotechnology Co., Ltd.)

Shanghai DuMa Biotechnology Co., Ltd.

发表刊物        影响因子           奖励金额
SCI期刊杂志      1.0≤1F<3.0          200元
SCI期刊杂志      3.0≤1F<6.0          400元
SCI期刊杂志      6.0≤1F<10.0         600元
SCI期刊杂志      1F≥10                1000元

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