Product Name

Anti-PI3K p85 alpha antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Gene Symbol

PIK3R1

Gene Synonyms

p85
AGM7
GRB1
IMD36
p85-ALPHA

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Gene Full Name

phosphoinositide-3-kinase regulatory subunit 1

Gene Summary

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

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Molecular Weight(MW)

84 kDa

Source

Rabbit

Cellular Localizatio

Cytoplasmic

Application Notes

WB:1:200-1:2000
IHC:1:200-1:1000

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.