Product Name

Anti-Occludin antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAWB

WB:1:200-1:2000

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Gene Symbol

OCLN

Gene Synonyms

BLCPMG
PTORCH1
PPP1R115

Gene Full Name

occludin

Gene Summary

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

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Molecular Weight(MW)

59 kDa

Source

Rabbit

Cellular Localizatio

Plasma membrane

Application Notes

WB:1:200-1:2000

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.