Product Profile

Product Name	Anti-CLDN2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CLDN2
Gene Synonyms	CLDN2 Claudin 2 SP82
Gene Full Name	claudin 2
Gene Summary	This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] More
Molecular Weight(MW)	25 kDa
Source	Rabbit
Cellular Localizatio	Cell junction > tight junction. Cell membrane.

Application

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WB

Western blot analysis using CLDN2 antibody against Jurkat (1), A549 (2) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CLDN2 antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of SK-OV-3 cells using CLDN2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.