Product Profile

Product Name	Anti-Smad6 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	SMAD6
Gene Synonyms	AOVD2 MADH6 MADH7 HsT17432 Hide
Gene Full Name	SMAD family member 6
Gene Summary	The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014] Hide
Molecular Weight(MW)	53 kDa
Source	Rabbit
Cellular Localizatio	Nucleus

Application

·        

WB

Western blot analysis using Smad6 antibody against A549 (1), Hela (2), Hep G2 (3), Jurkat (4) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using Smad6 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.