Product Profile

Product Name	Anti-CYP2R1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CYP2R1
Gene Synonyms	CYP2R1 Cytochrome P450 2R1
Gene Full Name	cytochrome P450 family 2 subfamily R member 1
Gene Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	57 KDa
Source	Rabbit
Cellular Localizatio	Endoplasmic reticulum, Membrane, Microsome

Application

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WB

Western blot analysis using CYP2R1 antibody against PC-3 (1) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using CYP2R1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Hela cells using CYP2R1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.