Product Profile

Product Name	Anti-JAK3 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	JAK3
Gene Synonyms	JAKL LJAK JAK-3 L-JAK JAK3_HUMAN Hide
Gene Full Name	Janus kinase 3
Gene Summary	The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	125 kDa（Observed 60 kDa）
Source	Rabbit
Cellular Localizatio	Cytoplasm, Membrane

Application

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WB

Western blot analysis using JAK3 antibody against Hela (1), HEK293 (2), KATO Ⅲ (3) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using JAK3 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of A549 cells using JAK3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.