Product Profile

Product Name	Anti-GAD1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	GAD1
Gene Synonyms	GAD SCP CPSQ1 DEE89 Hide
Gene Full Name	glutamate decarboxylase 1
Gene Summary	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	67 KDa
Source	Rabbit
Cellular Localizatio	plasma membrane

Application

·

WB

Western blot analysis using GAD1 antibody against PC-3(1), THp-1(2), 3T3-L1 (3), A431(4) cell lysate.

·

IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using GAD1 antibody with DAB staining.

·

ICC/IF

Immunofluorescence analysis of NIH/3T3 cells using GAD1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

 科研ELISA是上海笃玛生物的主营产品，科研ELISA栏目提供该类目产品说明书以及提供产品报价与网上订购。

上海笃玛生物科技有限公司经过数年的努力发展已迅速成为集产品研发、生产、经营为一体的专业化生物工程公司。公司具有完善的实验技术开发平台，成熟的抗原、抗体研发系统，熟练掌握各种酶联技术，结合公司的研发团队，可以有效的保证公司产品强的稳定性和高的准确性，同时又具有竞争力的价格。

公司目前主要提供生化试剂、分子生物学试剂及试剂盒，各种抗体及免疫学试剂盒、实验耗材等多门类上万种产品，产品涉及分子生物学、细胞生物学、免疫学等生命科学的各个领域。