Product Profile

Product Name	Anti-Tim3 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAWB
	WB:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	HAVCR2
Gene Synonyms	TIM3 CD366 KIM-3 SPTCL TIMD3 Tim-3 TIMD-3 HAVcr-2 Hide
Gene Full Name	hepatitis A virus cellular receptor 2
Gene Summary	The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] Hide
Molecular Weight(MW)	33kDa
Source	Rabbit
Cellular Localizatio	Plasma Membrane

Application

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WB

Western blot analysis using Tim3 antibody against Jurkat (1), A549 (2), MCF-7 (3), HT1080 (4) cell lysate.

Application Notes

WB:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.