产品展厅
Anti-WT1 antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:电询
  • 发布日期: 2024-08-21
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 电询
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-WT1 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Target Information

Gene Symbol

WT1

Gene Synonyms

GUD
AWT1
WAGR
WT33
NPHS4
WIT-2

Hide 

Gene Full Name

WT1 transcription factor

Gene Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]

Hide 

Molecular Weight(MW)

49 KDa

Source

Rabbit

Cellular Localizatio

Cytoplasm, Nucleus

Application

·        

WB

Western blot analysis using WT1 antibody against MCF-1 (1) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using WT1 antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of T24 cells using WT1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.



新闻资讯
联系方式
手机:15214367449
Q Q:
微信扫一扫