Product Profile

Product Name	Anti-SOD2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	SOD2
Gene Synonyms	SODM IPOB IPO-B MNSOD MVCD6 GClnc1 Mn-SOD Hide
Gene Full Name	superoxide dismutase 2
Gene Summary	This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016] Hide
Molecular Weight(MW)	25 KDa
Source	Rabbit
Cellular Localizatio	Mitochondrion

Application

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WB

Western blot analysis using SOD2 antibody against A431 (1), HepG2 (2), K562 (3) cell lysate.

·       

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using SOD2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Hela cells using SOD2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.