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| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-CCR7 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CCR7
Gene Synonyms
BLR2
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Gene Full Name
C-C motif chemokine receptor 7
Gene Summary
The protein encoded by this gene is a
member of the G protein-coupled receptor family. This receptor was identified
as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a
mediator of EBV effects on B lymphocytes. This receptor is expressed in
various lymphoid tissues and activates B and T lymphocytes. It has been shown
to control the migration of memory T cells to inflamed tissues, as well as
stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19
(CCL19/ECL) has been reported to be a specific ligand of this receptor.
Signals mediated by this receptor regulate T cell homeostasis in lymph nodes,
and may also function in the activation and polarization of T cells, and in
chronic inflammation pathogenesis. Alternative splicing of this gene results
in multiple transcript variants. [provided by RefSeq, Sep 2014]
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Molecular
Weight(MW)
43 KDa
Source
Rabbit
Cellular
Localizatio
Cell membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
EBI1
CCR-7
CD197
CDw197
CMKBR7
CC-CKR-7
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WB
Western blot analysis using CCR7 antibody against A431 (1), HepG2 (2) cell lysate.
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IHC
Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CCR7 antibody with DAB staining.
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ICC/IF
Immunofluorescence analysis of Hela cells using CCR7 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
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Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
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Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |