Product Profile

Product Name	Anti-TXNIP antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	TXNIP
Gene Synonyms	THIF VDUP1 ARRDC6 HHCPA78 EST01027 Hide
Gene Full Name	thioredoxin interacting protein
Gene Summary	This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] Hide
Molecular Weight(MW)	44 KDa
Source	Rabbit
Cellular Localizatio	Cytoplasm

Application

·        

WB

Western blot analysis using TXNIP antibody against HUVEC (1), MCF-7 (2) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using TXNIP antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.