产品展厅
Anti-PINCH antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:电询
  • 发布日期: 2024-08-26
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 电询
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-PINCH antibody

Antibody Type

Primary Antibodies

Immunogen

Recombinent Proteins

Key Feature

Clonality

Monoclonal

Isotype

IgG

Host Species

Mouse

Tested Application

ELISAICC/IFIHC

IHC:1:200-1:1000
ICC/IF:1:100-1:500

Species Reactivity

HumanRabbit

Concentration

1 mg/ml

Purification

Protein A

Target Information

Gene Symbol

LIMS1

Gene Synonyms

PINCH
PINCH1
PINCH-1

Gene Full Name

LIM zinc finger domain containing 1

Gene Summary

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

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Source

Mouse

Cellular Localizatio

Cell junction, Cell membrane, Membrane

Application

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung breast tissues using PINCH antibody with DAB staining.

·       

ICC/IF

Immunofluorescence analysis of A549cells using PINCH antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.


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