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| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti- PUMA antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
BBC3
Gene Synonyms
BBC3
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Gene Full Name
BCL2 binding component 3
Gene Summary
This gene encodes a member of the BCL-2
family of proteins. This family member belongs to the BH3-only pro-apoptotic
subclass. The protein cooperates with direct activator proteins to induce
mitochondrial outer membrane permeabilization and apoptosis. It can bind to
anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and
caspase activation. Because of its pro-apoptotic role, this gene is a
potential drug target for cancer therapy and for tissue injury. Alternative
splicing results in multiple transcript variants. [provided by RefSeq, Dec
2011]
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Source
Rabbit
Cellular
Localizatio
Mitochondrion
Application
ICC/IF:1:100-1:500
JFY1
PUMA
JFY-1
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PUMA antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using PUMA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:1000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |