Product Profile

Product Name	Anti-NMDAR1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	GRIN1
Gene Synonyms	NR1 MRD8 GluN1 NMDA1 NDHMSD NDHMSR NMD-R1 NMDAR1 Hide
Gene Full Name	glutamate ionotropic receptor NMDA type subunit 1
Gene Summary	The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	105 kDa（Observed:80 kDa）
Source	Rabbit
Cellular Localizatio	Cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Application

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WB

Western blot analysis using NMDAR1 antibody against MCF-1(1),HUVEC(2),HepG2(3),Caco(4) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer using NMDAR1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Hela cells using NMDAR1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.