Product Profile

Product Name	Anti-Hsp105 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	HSPH1
Gene Synonyms	HSP105 HSP105A HSP105B NY-CO-25 Hide
Gene Full Name	heat shock protein family H (Hsp110) member 1
Gene Summary	This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017] Hide
Molecular Weight(MW)	97 kDa
Cellular Localizatio	Cytoplasm

Application

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WB

Western blot analysis using Hsp105 antibody against HEK293(1), A549(2), MCF-1(3), HUVEC(4) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using Hsp105 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of SK-OV-3 cells using Hsp105 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.