Product Profile

Product Name	Anti-Gelsolin antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	GSN
Gene Synonyms	ADF AGEL GSN GELS Hide
Gene Full Name	gelsolin
Gene Summary	The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	86 kDa
Cellular Localizatio	Amyloid, Cytoplasm, Cytoskeleton, Secreted

Application

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WB

Western blot analysis using Gelsolin antibody against MCF-7(1), K562(2),HEK293(3),HUVEC(4) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using Gelsolin antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Hela cells using Gelsolin antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.