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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-FHIT antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
FHIT
Gene Synonyms
FRA3B
Gene Full Name
fragile histidine triad diadenosine
triphosphataseprovided
Gene Summary
The protein encoded by this gene is a
P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism.
This gene encompasses the common fragile site FRA3B on chromosome 3, where
carcinogen-induced damage can lead to translocations and aberrant
transcripts. In fact, aberrant transcripts from this gene have been found in
about half of all esophageal, stomach, and colon carcinomas. The encoded
protein is also a tumor suppressor, as loss of its activity results in
replication stress and DNA damage. [provided by RefSeq, Aug 2017]
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Cellular
Localizatio
Cytoplasm, Mitochondrion, Nucleus
Application
ICC/IF:1:100-1:500
AP3Aase
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using FHIT antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using FHIT antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:1000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |