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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MCM3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MCM3
Gene Synonyms
HCC5
More
Gene Full Name
minichromosome maintenance complex
component 3
Gene Summary
The protein encoded by this gene is one
of the highly conserved mini-chromosome maintenance proteins (MCM) that are
involved in the initiation of eukaryotic genome replication. The hexameric
protein complex formed by MCM proteins is a key component of the
pre-replication complex (pre_RC) and may be involved in the formation of
replication forks and in the recruitment of other DNA replication related
proteins. This protein is a subunit of the protein complex that consists of
MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein
also interacts with and is acetylated by MCM3AP, a chromatin-associated
acetyltransferase. The acetylation of this protein inhibits the initiation of
DNA replication and cell cycle progression. Several transcript variants
encoding different isoforms have been found for this gene. [provided by
RefSeq, Oct 2018]
More
Molecular
Weight(MW)
91 kDa
Cellular
Localizatio
Chromosome, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
P1.h
RLFB
P1-MCM3
·
WB
Western blot analysis using MCM3 antibody against Hela(1), Jurkat(2),HEK293(3),HepG2(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using MCM3 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using MCM3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |