Product Profile

Product Name	Anti-SUV39H1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	SUV39H1
Gene Synonyms	MG44 KMT1A SUV39H H3-K9-HMTase 1 More
Gene Full Name	SUV39H1 histone lysine methyltransferase
Gene Summary	This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. More
Molecular Weight(MW)	48 kDa
Cellular Localizatio	Centromere, Chromosome, Nucleus

Application

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WB

Western blot analysis using SUV39H1 antibody against MCF-7(1) cell lysate

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IHC

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using SUV39H1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of HELA cells using SUV39H1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.