产品展厅
Anti-PRKAB1 antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:OM641708
  • 发布日期: 2024-09-06
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 OM641708
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-PRKAB1 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHC

IHC:1:200-1:1000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Protein A

Target Information

Gene Symbol

PRKAB1

Gene Synonyms

AMPK
HAMPKb

Gene Full Name

protein kinase AMP-activated non-catalytic subunit beta 1

Gene Summary

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

More 

Molecular Weight(MW)

30 kDa

Cellular Localizatio

Cytosol, nucleoplasm, nucleus, cytoplasm

Application

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with DAB staining.

·       

IHC

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.



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