Product Profile

Product Name	Anti-FKBP51 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHC
	IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	FKBP5
Gene Synonyms	P54 AIG6 FKBP51 FKBP54 PPIase Ptg-10 Hide
Gene Full Name	FKBP prolyl isomerase 5
Gene Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants. Hide
Molecular Weight(MW)	51 kDa
Cellular Localizatio	Cytoplasm, Nucleus

Application

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using FKBP51 antibody with DAB staining.

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IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using FKBP51 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of Hela cells using FKBP51 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.