Product Profile

Product Name	Anti-UCH37 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	UCHL5
Gene Synonyms	UCH37 CGI-70 INO80R UCH-L5 Hide
Gene Full Name	ubiquitin C-terminal hydrolase L5
Gene Summary	Enables endopeptidase inhibitor activity; proteasome binding activity; and thiol-dependent deubiquitinase. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of smoothened signaling pathway; and protein deubiquitination. Located in cytosol; nucleolus; and nucleoplasm. Colocalizes with Ino80 complex. Hide
Molecular Weight(MW)	38 kDa
Cellular Localizatio	Cytoplasm, Nucleus, Proteasome

Application

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WB

Western blot analysis using UCH37 antibody against HepG2(1) cell lysate.

·       

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using UCH37 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of CAL-27 cells using UCH37 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.