Product Profile

Product Name	Anti-TLE1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	TLE1
Gene Synonyms	ESG ESG1 GRG1 TLE-1 Hide
Gene Full Name	TLE family member 1, transcriptional corepressor
Gene Summary	Enables identical protein binding activity and transcription corepressor activity. Involved in negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of anoikis; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022] Hide
Molecular Weight(MW)	83KD
Cellular Localizatio	Nucleus

Application

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WB

Western blot analysis using TLE1 antibody against MCF-7(1), HepG2(2) ), HEK293(3) cell lysate

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using TLE1 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.