产品展厅
Anti-CRTC2 antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:OM641708
  • 发布日期: 2024-09-10
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 OM641708
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-CRTC2 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHC

IHC:1:200-1:2000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1mg/ml

Purification

Protein A

Target Information

Gene Symbol

CRTC2

Gene Synonyms

TORC2
TORC-2

Gene Full Name

CREB regulated transcription coactivator 2

Gene Summary

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

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Molecular Weight(MW)

73KD

Cellular Localizatio

Cytoplasm, Nucleus

Application

·        

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CRTC2 antibody with DAB staining.

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CRTC2 antibody with DAB staining.

·        

ICC/IF

Immunofluorescence analysis of NIH3T3 cells using CRTC2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:2000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.


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