Product Profile

Product Name	Anti-c-Rel antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	REL
Gene Synonyms	C-Rel IMD92 HIVEN86A
Gene Full Name	REL proto-oncogene, NF-kB subunit
Gene Summary	This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] Hide
Molecular Weight(MW)	69KD
Cellular Localizatio	Nucleus

Application

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WB

Western blot analysis using c-Rel antibody against A549(1) cell lysate.

        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using c-Rel antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.