Product Profile

Product Name	Anti-Tyrosinase antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	TYR
Gene Synonyms	ATN CMM8 OCA1 OCA1A OCAIA SHEP3 Hide
Gene Full Name	tyrosinase
Gene Summary	The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008] Hide
Molecular Weight(MW)	60KD（Observed:80 kD）
Cellular Localizatio	Melanosome membrane

Application

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WB

Western blot analysis using Tyrosinase antibody against K562(1) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using Tyrosinase antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of MG-63 cells using Tyrosinase antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.