Product Profile

Product Name	Anti-Aurora B antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHC
	IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	AURKB
Gene Synonyms	AIK2 AIM1 ARK2 AurB IPL1 STK5 AIM-1 ARK-2 STK-1 STK12 PPP1R48 aurkb-sv1 aurkb-sv2 Hide
Gene Full Name	aurora kinase B
Gene Summary	This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] Hide
Molecular Weight(MW)	39KD
Cellular Localizatio	Centromere, Chromosome, Cytoplasm, Cytoskeleton, Nucleus

Application

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IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using Aurora B antibody with DAB staining.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using Aurora B antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of MG63 cells using Aurora B antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.