Product Profile

Product Name	Anti-OPA1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHC
	IHC:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	OPA1
Gene Synonyms	NPG NTG MGM1 BERHS largeG MTDPS14 Hide
Gene Full Name	OPA1 mitochondrial dynamin like GTPase
Gene Summary	The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017] Hide
Molecular Weight(MW)	112KD
Cellular Localizatio	Membrane, Mitochondrion, Mitochondrion inner membrane

Application

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using OPA1 antibody with DAB staining.

        

IHC

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using OPA1 antibody with DAB staining.

Application Notes

IHC:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.