Product Profile

Product Name	Anti-OLIG2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHC
	IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	OLIG2
Gene Synonyms	BHLHB1 OLIGO2 RACK17 PRKCBP2 bHLHe19 Hide
Gene Full Name	oligodendrocyte transcription factor 2
Gene Summary	This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	32KD
Cellular Localizatio	Cytoplasm, Nucleus

Application

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IHC

Immunohistochemical analysis of paraffin-embedded brain tissues using Olig2 antibody with DAB staining.

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IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using Olig2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of A549 cells using Olig2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.