Product Profile

Product Name	Anti-HDAC2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	HDAC2
Gene Synonyms	HD2 RPD3 YAF1 KDAC2 Hide
Gene Full Name	histone deacetylase 2
Gene Summary	This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] Hide
Molecular Weight(MW)	55KD
Cellular Localizatio	Cytoplasm, Nucleus

Application

·        

WB

Western blot analysis using HDAC2 antibody against NIH3T3(1) cell lysate.

·       

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using HDAC2 antibody with DAB staining.

·        

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using HDAC2 antibody with DAB staining.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.