产品展厅
Anti-CYP1A1 antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:OM641708
  • 发布日期: 2024-09-12
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 OM641708
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-CYP1A1 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAIHCWB

WB:1:200-1:2000
IHC:1:200-1:200

Species Reactivity

HumanMouseRat

Concentration

1mg/ml

Purification

Protein A

Target Information

Gene Symbol

CYP1A1

Gene Synonyms

AHH
AHRR
CP11
CYP1
CYPIA1
P1-450
P450-C
P450DX

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Gene Full Name

cytochrome P450 family 1 subfamily A member 1

Gene Summary

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

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Molecular Weight(MW)

58KD

Cellular Localizatio

Cytoplasm, Endoplasmic reticulum, Membrane, Microsome, Mitochondrion, Mitochondrion inner membrane

Application

·        

WB

Western blot analysis using CYP1A1 antibody against HepG2(1), Hela(2) cell lysate.

·        

IHC

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using CYP1A1 antibody with DAB staining.

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CYP1A1 antibody with DAB staining.

Application Notes

WB:1:200-1:2000
IHC:1:200-1:200

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.


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