Product Profile

Product Name	Anti-RSK2 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	RPS6KA3
Gene Synonyms	CLS RSK HU-3 RSK2 MRX19 ISPK-1 XLID19 p90-RSK2 pp90RSK2 MAPKAPK1B S6K-alpha3 Hide
Gene Full Name	ribosomal protein S6 kinase A3
Gene Summary	This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	84KD
Cellular Localizatio	Cytoplasm, Nucleus

Application

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WB

Western blot analysis using RSK2 antibody against HepG2(1) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded breast cancer using RSK2 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of A549 cells using RSK2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.