产品展厅
Anti-PPP1CA antibody
  • 品牌:OminimAbs
  • 产地:上海
  • 型号:毫升
  • 货号:OM641708
  • 发布日期: 2024-09-12
  • 更新日期: 2024-10-09
产品详请
产地 上海
品牌 OminimAbs
保存条件
货号 OM641708
用途 实验研究
应用范围 科研实验
抗原来源 电询
保质期 2年
抗体名 电询
是否单克隆
克隆性
靶点 电询
适应物种 电询
形态 电询
宿主 电询
标记物 电询
包装规格 毫升
亚型 电询
标识物 电询
浓度 电询%
免疫原 电询
是否进口

Product Profile

Product Name

Anti-PPP1CA antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Application

ELISAICC/IFIHC

IHC:1:200-1:2000
ICC/IF:1:100-1:500

Species Reactivity

HumanMouseRat

Concentration

1mg/ml

Purification

Protein A

Target Information

Gene Symbol

PPP1CA

Gene Synonyms

PP1A
PP-1A
PPP1A
PP1alpha

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Gene Full Name

protein phosphatase 1 catalytic subunit alpha

Gene Summary

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020]

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Molecular Weight(MW)

38KD

Cellular Localizatio

Cytoplasm, Nucleus

Application

·        

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PPP1CA antibody with DAB staining.

·        

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PPP1CA antibody with DAB staining.

·        

ICC/F

Immunofluorescence analysis of A549 cells using PPP1CA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

IHC:1:200-1:2000
ICC/IF:1:100-1:500

Additional Information

Form

Liquid

Storage Instruction

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.

Storage Buffer

Purified antibody in PBS with 0.05% sodium azide.


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